About Topotarget A/S
Topotarget A/S (NASDAQ OMX: TOPO) is a Scandinavian-based,
international biotech company headquartered in Denmark, dedicated
to improving cancer therapies. In collaboration with Spectrum
Pharmaceuticals, Inc, Topotarget currently focuses on the
development in pivotal studies of our lead HDACi, belinostat, which
has demonstrated a clear anti-neoplastic effect in both
hematological malignancies and solid tumors. Belinostat can be used
in combination with full doses of chemotherapy, and is currently in
a pivotal trial within peripheral T-cell lymphoma (PTCL) and phase
II in cancer of unknown primary (CUP).
The company counts ~23 employees, covering expertise in a wide
spectrum within drug
development through to commercialization. Topotarget's core
scientific expertise lies in the biological mechanisms underlying
DNA damage control (topoisomerase II), chromatin replication
control, and cell cycle regulation.